Human Sortilin / SORT1 Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-SON-H52H5-100UG
Supplier Catalog Number:
SON-H52H5-100ug
Alternative Catalog Number:
ABS-SON-H52H5-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
The Sortilin is a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose6phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptorligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. - Proteine/Peptide
