Its been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizingantibody and Tcell responses, as well as protective immunity. - Antikörper
Tag:
Mouse IgG1 | Mouse Kappa
Buffer:
PBS, pH7.4
Purity:
0.95
Form:
Powder
Target:
Spike RBD
Immobilized SARS-CoV-2 Spike RBD Protein, His Tag (XBB.1.5/Omicron) (MALS verified) (Cat. No. SPD-C5242) and SARS-CoV-2 Spike RBD Protein, His Tag (XBB/Omicron) (MALS verified) (Cat. No. SPD-C5241) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (9A6A11) (XBB.1.5/Omicron Specific) (Cat. No. SPD-Y168) with a linear range of 0.195-12.5ng/mL. The antibody does not bind Spike RBD of WT (Cat. No. SPD-C52H3), Alpha (Cat. No. SPD-C52Hn), Beta (Cat. No. SPD-C52Hp), Gamma (Cat. No. SPD-C52Hr), Delta (Cat. No. SPD-C52Hh), B.1.1.529/Omicron (Cat. No. SPD-C522e), BA.2/Omicron (Cat. No. SPD-C522g), BA.3/Omicron, BA.4&5Omicron (Cat. No. SPD-C522r), BA.2.12.1/Omicron, BA.2.75/Omicron (Cat. No. SPD-C522t), BF.7&BA.4.6/Omicron (Cat. No. SPD-C522y) and BQ.1.1/Omicron (Cat. No. SPD-C5240) (QC tested).
Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (9A6A11) (XBB.1.5/Omicron Specific) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.
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