SARS-CoV-2 Spike Trimer Protein (G75V, T76I, SYLTPGD 247-253 del, L452Q, F490S, D614G, T859N), His Tag (MALS verified), Unconjugated, Human

Product Overview

• Article Name: SARS-CoV-2 Spike Trimer Protein (G75V, T76I, SYLTPGD 247-253 del, L452Q, F490S, D614G, T859N), His Tag (MALS verified), Unconjugated, Human
• Biozol Catalog Number: ABS-SPN-C52HS-50UG
• Supplier Catalog Number: SPN-C52Hs-50ug
• Alternative Catalog Number: ABS-SPN-C52HS-50UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Virus
• Conjugation: Unconjugated
• Alternative Names: sars-cov-2

Product Description

SARSCoV2 Spike Trimer, His Tag (SPNC52Hs) is the ectodomain of SARSCoV2 spike protein which contains AA Val 16 Pro 1213 (Accession QHD43416.1). Mutations G75V, T76I, SYLTPGD 247253 del, L452Q, F490S, D614G, T859N were identified in the SARSCoV2 Lambda variant (Pango lineage: C.37). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the Cterminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARSCoV2 S protein and abolish the furin cleavage site, respectively. - Proteine/Peptide

Product Properties

• Molecular Weight: 137.3 kDa
• Tag: C-10*His
• NCBI: 43416
• Buffer: 0.1 M Sodium citrate, pH5.5
• Purity: 95%
• Form: Powder
• Target: Spike protein

Images

Immobilized SARS-CoV-2 Spike Trimer, His Tag (Cat. No. SPN-C52Hs) at 1 µg/mL (100 µL/well) can bind Human ACE2, Fc Tag (Cat. No. AC2-H5257) with a linear range of 0.1-6 ng/mL (QC tested).

Immobilized SARS-CoV-2 Spike Trimer, His Tag (Cat. No. SPN-C52Hs) at 1 µg/mL (100 µL/well) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (Cat. No. S1N-M122) with a linear range of 0.1-3 ng/mL (Routinely tested).

SARS-CoV-2 Spike Trimer, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.