Human TDP-43 Protein, His Tag, Unconjugated, E. coli 100 ug

Product Overview

• Article Name: Human TDP-43 Protein, His Tag, Unconjugated, E. coli 100 ug
• Biozol Catalog Number: ABS-TD3-H5145-100UG
• Supplier Catalog Number: TD3-H5145-100ug
• Alternative Catalog Number: ABS-TD3-H5145-100UG
• Manufacturer: AcroBiosystems
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

TDP43, the transactive response (TAR)DNA binding Protein with a molecular weight of 43 KDa is encoded by TARDBP gene that located at the chromosome 1. It is a RNA/DNA binding protein that structurally resembles a typical hnRNP protein family member. involved in transcriptional regulation and RNA processing. It is linked to sporadic and familial amyotrophic lateral sclerosis and frontotemporal lobar degeneration. TDP43 is predominantly nuclear, but it translocates to the cytoplasm under pathological conditions. Cytoplasmic accumulation, phosphorylation, ubiquitination and truncation of TDP43 are the main hallmarks of TDP43 proteinopathies. - Proteine/Peptide

Product Properties

• Molecular Weight: 46.8 kDa
• Tag: N-10*His
• NCBI: 13148
• Buffer: 50 mM HEPES, 500 mM NaCl, 0.4 M Arginine, pH8.0
• Purity: 90%
• Form: Liquid
• Target: TDP-43

Images

Immobilized Human TDP-43, His Tag (Cat. No. TD3-H5145) at 1 µg/mL (100 µL/well) can bind Anti-TDP43 Antibody with a linear range of 0.2-3 ng/mL (QC tested).

Human TDP-43, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.