Human Latent TGF-beta 3 / Latent TGFB3 Protein, His Tag, Unconjugated
Biozol Catalog Number:
ABS-TG3-H52H5-1MG
Supplier Catalog Number:
TG3-H52H5-1mg
Alternative Catalog Number:
ABS-TG3-H52H5-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Transforming growth factor beta 3 ( TGFB3) is also known as TGFbeta3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGFbeta 3 is similar with TGFbeta 1 and beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelialmesenchymal transition. TGFbeta3 is released from LAP by integrins: integrinbinding results in distortion of the LAP chain and subsequent release of the active TGFbeta3. Once activated following release of LAP, TGFbeta3 acts by binding to TGFbeta receptors (TGFBR1 and TGFBR2), which transduce signal. - Proteine/Peptide
