Human Thrombospondin-2 Protein, His Tag, Unconjugated
Biozol Catalog Number:
ABS-TH2-H52H5-100UG
Supplier Catalog Number:
TH2-H52H5-100ug
Alternative Catalog Number:
ABS-TH2-H52H5-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Thrombospondin2 is also known as THBS2, TSP2, TSP2. Thrombospondin2 (TSP2) is an antiangiogenic matricellular protein that inhibits tumor growth and angiogenesis. Adhesive glycoprotein that mediates celltocell and celltomatrix interactions. Ligand for CD36 mediating antiangiogenic properties. 2 SNPs in the intron region of THBS2 gene (rs6422747 and rs6422748) were associated with susceptibility of IDD. However, they were not related with severity of IDD, including the total number of degenerative disc and level of IDD. Thrombospondin 2, an important regulator of synaptogenesis in central nervous system development, was distributed in retinal macroglia cells, and its receptor alpha2delta1 was in retinal neurons. activated macroglia cells may participate in alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure, and macrogliaderived thrombospondin 2 may modulate these changes via binding to its neuronal receptor alpha2delta1. - Proteine/Peptide
