Biotinylated Human TIGIT Protein, His,Avitag(TM), active dimer (recommended for biopanning) (MALS verified)

Product Overview

• Article Name: Biotinylated Human TIGIT Protein, His,Avitag(TM), active dimer (recommended for biopanning) (MALS verified)
• Biozol Catalog Number: ABS-TIT-H82E6-200UG
• Supplier Catalog Number: TIT-H82E6-200ug
• Alternative Catalog Number: ABS-TIT-H82E6-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Tcell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as Vset and immunoglobulin domaincontaining protein 9 (VSIG9), Vset and transmembrane domaincontaining protein 3 (VSTM3),which belongs to singlepass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosinebased inhibitory motif (ITIM). TIGIT is expressed at low levels on peripheral memory and regulatory CD4+ Tcells and NK cells and is upregulated following activation of these cells (at protein level). TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses Tcell activation by promoting the generation of mature immunoregulatory dendritic cells. - Proteine/Peptide

Product Properties

• Molecular Weight: 30.5 kDa
• Tag: C-10*His & C-Avi
• NCBI: 495
• Buffer: PBS, pH7.4
• Expression System: Met 22 - Pro 141
• Purity: 90%
• Form: Powder
• Target: TIGIT

Application Notes

• Application Notes: TIT-H82E6 works best for experiments that test the binding between TIGIT and candidate antibodies, such as biopanning and other relevant assays. This product is NOT suitable for testing TIGIT-CD155 binding. For this type of application, we strongly recommend you to choose TIT-H82F1 as an alternative.

Images

TIT-H82E6-200ug