Biotinylated Mouse TNF-alpha Protein, His,Avitag(TM), active trimer (MALS verified), Human
Biozol Catalog Number:
ABS-TNA-M82E9-200UG
Supplier Catalog Number:
TNA-M82E9-200ug
Alternative Catalog Number:
ABS-TNA-M82E9-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Mouse
Conjugation:
Biotin
Tumor necrosis factor alpha (TNFalpha) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFalpha is in the regulation of immune cells. TNFalpha is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFalpha production has been implicated in a variety of human diseases, including major depression, Alzheimers disease and cancer. Recombinant TNFalpha is used as an immunostimulant under the INN tasonermin. TNFalpha can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated. - Proteine/Peptide
