Human DcR3 / TNFRSF6B Protein, Fc Tag, Unconjugated
Biozol Catalog Number:
ABS-TNB-H5255-1MG
Supplier Catalog Number:
TNB-H5255-1mg
Alternative Catalog Number:
ABS-TNB-H5255-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFRCys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL and LIGHTmediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. - Proteine/Peptide