Human TOP2A / TOP2 Protein, Tag Free, Unconjugated, E. coli

Product Overview

• Article Name: Human TOP2A / TOP2 Protein, Tag Free, Unconjugated, E. coli
• Biozol Catalog Number: ABS-TOA-H5117-500UG
• Supplier Catalog Number: TOA-H5117-500ug
• Alternative Catalog Number: ABS-TOA-H5117-500UG
• Manufacturer: AcroBiosystems
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

DNA topoisomerase 2alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes doublestrand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anticancer drugs that cause treatmentrelated leukemias with balanced translocations. - Proteine/Peptide

Product Properties

• Molecular Weight: 13.0 kDa
• Tag: Native
• NCBI: 11388
• Buffer: 50 mM Tris, 0.5 M KCl, pH8.0
• Expression System: Ser 1354 - Ser 1473
• Purity: 90%
• Form: Liquid
• Target: TOP2A

Images

TOA-H5117-500ug