Anti-Trastuzumab Antibody, Mouse IgG1 (6F2F7-2) (recommended for PK/PD), Unconjugated, Human
Biozol Catalog Number:
ABS-TRB-Y5B-100UG
Supplier Catalog Number:
TRB-Y5b-100ug
Alternative Catalog Number:
ABS-TRB-Y5B-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Antikörper
Species Reactivity:
Mouse
Conjugation:
Unconjugated
Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cellbased assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein. - Antikörper
Tag:
Mouse IgG1 | Mouse kappa
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Purity:
0.95
Form:
Powder
Target:
Trastuzumab
Immobilized Trastuzumab at 1 µg/mL (100 µL/well) can bind Anti-Trastuzumab Antibody, Mouse IgG1 (6F2F7-2) (Cat. No. TRB-Y5b) with a linear range of 0.19-6.25 ng/mL (QC tested).
Serial dilutions of Anti-Trastuzumab Antibody, Mouse IgG1 (6F2F7-2) ( Cat. No. TRB-Y5b) was detected by Biotinylated Human Her2, His,Avitag (Cat. No. HE2-H82E2) with a half maximal inhibitory concentration (IC50) of 7.02 µg/mL (Routinely tested).
Anti-Trastuzumab Antibody, Mouse IgG1 (6F2F7-2) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.
TRB-Y5b-100ug
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