Rat uPAR / PLAUR Protein, His Tag, Unconjugated, Human
Biozol Catalog Number:
ABS-UPR-R52H3-1MG
Supplier Catalog Number:
UPR-R52H3-1mg
Alternative Catalog Number:
ABS-UPR-R52H3-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Rat
Conjugation:
Unconjugated
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cellsurface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptorbound proenzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosylphosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxyterminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several posttranslational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008] - Proteine/Peptide
