Human USP1 & UAF1 Protein, GST Tag&Strep II Tag, Unconjugated, Insect

Product Overview

• Article Name: Human USP1 & UAF1 Protein, GST Tag&Strep II Tag, Unconjugated, Insect
• Biozol Catalog Number: ABS-US1-H85W3-1MG
• Supplier Catalog Number: US1-H85W3-1mg
• Alternative Catalog Number: ABS-US1-H85W3-1MG
• Manufacturer: AcroBiosystems
• Host: Insect
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

USP1 (ubiquitin-specific protease 1) is a deubiquitinating enzyme crucial for DNA damage repair, cell cycle regulation, and protein homeostasis. Its catalytic efficiency is markedly enhanced by UAF1 (USP1-associated factor 1), a cofactor that stabilizes USP1 and directs it to nuclear substrates. Together, the USP1-UAF1 complex removes ubiquitin from key proteins such as PCNA and FANCD2, maintaining genomic stability and influencing cancer development, making it a potential therapeutic target in oncology. - Proteine/Peptide

Product Properties

• Molecular Weight: 114.1 kDa & 77.8 kDa
• Tag: N-GST | C-Strep II
• NCBI: 94782
• Buffer: 50 mM Tris, 150 mM NaCI, pH7.5
• Expression System: Pro 2 - Leu 785 & Ala 2 - Thr 677
• Purity: 95%
• Form: Liquid
• Target: USP1 & UAF1

Images

US1-H85W3-1mg