Biotinylated Cynomolgus VCAM-1 / CD106 Protein, His,Avitag(TM) (MALS verified), Human
Biozol Catalog Number:
ABS-VC1-C82E3-25UG
Supplier Catalog Number:
VC1-C82E3-25ug
Alternative Catalog Number:
ABS-VC1-C82E3-25UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Conjugation:
Biotin
Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Iglike C2type (immunoglobulinlike) domains. CD106 / VCAM1 is expressed on inflammed vascular endothelium, as well as on macrophagelike and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM1 is Important in cellcell recognition and appears to function in leukocyteendothelial cell adhesion. CD106 / VCAM1 interacts with the beta1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM100 / VCAM1 binds to ECMVD capsid proteins and acts as a receptor for this virus. - Proteine/Peptide
Immobilized Human ITGA4&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52W1) at 5 µg/mL (100 µL/well) can bind Biotinylated Cynomolgus VCAM-1 Protein, His,Avitag (Cat. No. VC1-C82E3) with a linear range of 0.2-5 ng/mL (QC tested).
Biotinylated Cynomolgus VCAM-1 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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