Human VCAM-1 / CD106 Protein, His Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human VCAM-1 / CD106 Protein, His Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-VC1-H5224-1MG
• Supplier Catalog Number: VC1-H5224-1mg
• Alternative Catalog Number: ABS-VC1-H5224-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Iglike C2type (immunoglobulinlike) domains. CD106 / VCAM1 is expressed on inflammed vascular endothelium, as well as on macrophagelike and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM1 is Important in cellcell recognition and appears to function in leukocyteendothelial cell adhesion. CD106 / VCAM1 interacts with the beta1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM100 / VCAM1 binds to ECMVD capsid proteins and acts as a receptor for this virus. - Proteine/Peptide

Product Properties

• Molecular Weight: 74.9 kDa
• Tag: C-6*His
• NCBI: 001069
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: VCAM-1

Images

Immobilized Human VCAM-1, His Tag (Cat. No. VC1-H5224) at 5 µg/mL (100 µL/well) can bind Biotinylated Human ITGA4&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT1-H82W1) with a linear range of 4-78 ng/mL (QC tested).

Human VCAM-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.