Chromogranin A / CHGA (Neuroendocrine Marker) Antibody - With BSA and Azide, Clone: [CGA/413 + CHGA/777 + CHGA/798], Mouse, Monoclonal
Biozol Catalog Number:
ABT-AH11076-U0020
Supplier Catalog Number:
AH11076-U0020
Alternative Catalog Number:
ABT-AH11076-U0020-20UG
Manufacturer:
Abcepta
Host:
Mouse
Category:
Antikörper
Application:
FC, IF, IHC
Species Reactivity:
Human, Mouse, Porcine, Rat
Alternative Names:
Chromogranin-A, CgA, Pituitary secretory protein I, SP-I, Vasostatin-1, Vasostatin I, Vasostatin-2, Vasostatin II, EA-92, ES-43, Pancreastatin, SS-18, WA-8, WE-14, LF-19, AL-11, GV-19, GR-44, ER-37, CHGA
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
