Anti-Topoisomerase II alpha Antibody, Clone: [TOP2A/1362], Mouse, Monoclonal
Biozol Catalog Number:
ABT-AH13548-U0100
Supplier Catalog Number:
AH13548-U0100
Alternative Catalog Number:
ABT-AH13548-U0100-100UG
Manufacturer:
Abcepta
Host:
Mouse
Category:
Antikörper
Application:
FC, IF, IHC-P, WB
Species Reactivity:
Human
Alternative Names:
ATP hydrolyzing DNA topoisomerase II alfa, DNA gyrase, DNA topoisomerase (ATP hydrolyzing), DNA topoisomerase 2 alpha, DNA topoisomerase II 170kD, DNA topoisomerase II alpha, DNA Topoisomerase2, TOP2A, Topoisomerase DNA II alpha 170kDa, TP2A
It recognizes a 170kDa protein, which is identified as topoisomerase II. shows no cross-reaction with Topoisomerase II or I. Topo II plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo II is also implicated in drug resistance of tumor cells.
