NR3C1 Antibody, Clone: [740CT12.1.5], Mouse, Monoclonal

Product Overview

• Article Name: NR3C1 Antibody, Clone: [740CT12.1.5], Mouse, Monoclonal
• Biozol Catalog Number: ABT-AM2187B
• Supplier Catalog Number: AM2187b
• Alternative Catalog Number: ABT-AM2187B-400UL
• Manufacturer: Abcepta
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse
• Alternative Names: Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL

Product Description

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation (By similarity).

Product Properties

• Clonality: Monoclonal
• Clone Designation: [740CT12.1.5]
• Molecular Weight: 85659
• NCBI: 2908
• UniProt: P04150
• Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
• Target: This NR3C1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from human NR3C1.