Anti-COBRA1 (NELF-B) Antibody, IgG1, Clone: [F7E4], Mouse, Monoclonal

Catalog Number: ABT-AN1339
Article Name: Anti-COBRA1 (NELF-B) Antibody, IgG1, Clone: [F7E4], Mouse, Monoclonal
Biozol Catalog Number: ABT-AN1339
Supplier Catalog Number: AN1339
Alternative Catalog Number: ABT-AN1339-100UL
Manufacturer: Abcepta
Host: Mouse
Category: Antikörper
Alternative Names: A730008L03Rik antibody, AB041607 antibody, AI663983 antibody, Cofactor of BRCA1 antibody, DKFZp586B0519 antibody, KIAA1182 antibody, Negative elongation factor B antibody, Negative elongation factor protein B antibody, Nelf b antibody, NELF-B antibody, NELFB antibody, RGD1307832 antibody, RP13-122B23.3 antibody, RP23-132N23.4 antibody
COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERalpha) and repress ERalpha-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)
Clonality: Monoclonal
Clone Designation: [F7E4]
Molecular Weight: 65697
Isotype: IgG1
NCBI: 25920
UniProt: Q8WX92
Form: Protein G Purified
Target: COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERalpha) and repress ERalpha-mediated transcription (Aiyar SE et a