Anti-DENND3 (Thr450) Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AN1357
Article Name: Anti-DENND3 (Thr450) Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AN1357
Supplier Catalog Number: AN1357
Alternative Catalog Number: ABT-AN1357-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Alternative Names: DENN Domain Containing 3, DENN Domain-Containing Protein 3, DENN/MADD Domain Containing 3, KIAA0870 DENN/MADD domain containing 3, KIAA0870DENN domain-containing protein 3
The DENN (differentially expressed in normal and neoplastic cells) domain (DENND) is a poorly characterized protein module conserved throughout evolution (McPherson et al., 2011). Proteins bearing a DENN domain have recently emerged as the largest family of Rab GEFs. Among these DENN domain proteins, DENND3 is a GEF for Rab12, promoting the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form (McPherson and Xu, 2015, Matsui et al., 2011).
Clonality: Polyclonal
Molecular Weight: 135890
NCBI: 22898
UniProt: A2RUS2
Form: Antigen Affinity Purified from Pooled Serum
Target: The DENN (differentially expressed in normal and neoplastic cells) domain (DENND) is a poorly characterized protein module conserved throughout evolution (McPherson et al., 2011). Proteins bearing a DENN domain have recently emerged as the largest family