Anti-Dopamine Transporter (Thr53) Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AN1366
Article Name: Anti-Dopamine Transporter (Thr53) Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AN1366
Supplier Catalog Number: AN1366
Alternative Catalog Number: ABT-AN1366-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Alternative Names: DA transporter antibody, DAT 1 antibody, DAT antibody, DAT1 antibody, Dopamine transporter 1 antibody, Dopamine transporter antibody, PKDYS antibody, SC6A3_HUMAN antibody, SLC6A3 antibody, Sodium dependent dopamine transporter antibody, Sodium-dependent dopamine transporter antibody, Solute carrier family 6 (neurotransmitter transporter dopamine) member 3 antibody, Solute carrier family 6 (neurotransmitter transporter) member 3 antibody, Solute carrier family 6 member 3 antibody, Variable number tandem repeat (VNTR) antibody
The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinsons disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996). It has been shown that phosphorylation at Thr-53 directly affects dopamine influx and amphetamine-stimulated substrate efflux, indicating that the Thr-53 residue plays a major role in transport activity (Foster et al., 2012).
Clonality: Polyclonal
Molecular Weight: 68746
NCBI: 24898
UniProt: P23977
Form: Antigen Affinity Purified from Pooled Serum
Target: The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neuron