coagulation factor V/VIII-homology domains protein 1, DCBLD2, CUB and LCCL domain-containing protein 2, Discoidin, Endothelial and smooth muscle cell-derived neuropilin-like protein
A novel protein ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues, particularly highly expressed in cultured vascular smooth muscle cells. ESDN is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins.