Anti-TRAIL R3 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AN2126
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| Article Name: | Anti-TRAIL R3 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AN2126 |
| Supplier Catalog Number: | AN2126 |
| Alternative Catalog Number: | ABT-AN2126-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Alternative Names: | TNFRSF10C, DCR1, LIT, TRAILR3, TRID, UNQ321/PRO366 |
| DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis. |
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