Anti-CLAC-P (NC2-1 region) Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AN2127
- Images (0)
| Article Name: | Anti-CLAC-P (NC2-1 region) Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AN2127 |
| Supplier Catalog Number: | AN2127 |
| Alternative Catalog Number: | ABT-AN2127-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Alternative Names: | COL25A1, Collagen alpha-1 XXV chain, Alzheimer disease amyloid-associated protein, AMY, Collagen-like Alzheimer amyloid plaque component |
| Antibodies against senile plaque (SP) amyloid obtained a clone 9D2, which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimers disease (AD) brains. The 9D2 antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD |
Product Guarantee and Expert Support
