STE20-related kinase adapter protein beta, STRAD beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog, ILP-interacting protein homolog, Polyploidy-associated protein kinase, Pseudokinase ALS2CR2, Stradb
A novel protein kinase, polyploidy-associated protein kinase (PAPK) is a new member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival. Activation of a death signal transduction pathway may result in the stimulation of the PAPK promoter, which leads to increased PAPK expression and provides a negative feedback signal that prevents cell death.