Anti-CIDE3 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AN2132
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| Article Name: | Anti-CIDE3 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AN2132 |
| Supplier Catalog Number: | AN2132 |
| Alternative Catalog Number: | ABT-AN2132-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Alternative Names: | CIDEC, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, Lipid transferase CIDEC |
| DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis. |
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