Anti-Alivin1 (AMIGO2) Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AN2142
Article Name: Anti-Alivin1 (AMIGO2) Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AN2142
Supplier Catalog Number: AN2142
Alternative Catalog Number: ABT-AN2142-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Alternative Names: AMIGO2, Differentially expressed in gastric adenocarcinomas, ALI1
A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane domain, and display homology to Kek and Trk families. Results suggest that expression of ali1 promotes depolarization-dependent survival of the granule neuron. Mouse ali1 was mapped to a locus approximately 55.3 cM from the centromere on chromosome 15 that is syntenic to positional candidate loci for familial Alzheimers disease type 5 and Parkinsons disease 8 on human chromosome 12.
Clonality: Polyclonal
Molecular Weight: 57934
NCBI: 347902
UniProt: Q86SJ2