Anti-GluR1 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AN2171
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| Article Name: | Anti-GluR1 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AN2171 |
| Supplier Catalog Number: | AN2171 |
| Alternative Catalog Number: | ABT-AN2171-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Alternative Names: | GRIA1, Glutamate receptor 1, AMPA-selective glutamate receptor 1, Glutamate receptor ionotropic, AMPA 1, GluR-K1, GluR-A, GLUH1 |
| L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The Glutamate Receptor, Metabotropic, 1, (mGluR1 alpha) activates phospholipase C and participates in the central action of glutamate in the central nervous system, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum |
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