Mouse Ern1 Antibody (C-term), Clone: [RB34474], Rabbit, Polyclonal

Product Overview

• Article Name: Mouse Ern1 Antibody (C-term), Clone: [RB34474], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP14250B
• Supplier Catalog Number: AP14250b
• Alternative Catalog Number: ABT-AP14250B-400UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Mouse
• Alternative Names: Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, 3126-, Ern1 {ECO:0000312|MGI:MGI:1930134}

Product Description

Ern1 senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Product Properties

• Clonality: Polyclonal
• Clone Designation: [RB34474]
• Molecular Weight: 110185
• NCBI: 78943
• UniProt: Q9EQY0
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target: This Mouse Ern1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 827-855 amino acids from the C-terminal region of mouse Ern1.
• Antibody Type: Polyclonal Antibody

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