CD10 antibody, Clone: [R03643], Rabbit, Polyclonal

Product Overview

• Article Name: CD10 antibody, Clone: [R03643], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP22424A
• Supplier Catalog Number: AP22424a
• Alternative Catalog Number: ABT-AP22424A-200UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse
• Alternative Names: Neprilysin, 3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME {ECO:0000303|PubMed:27588448, ECO:0000312|HGNC:HGNC:7154}

Product Description

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:6349683, PubMed:6208535, PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu- enkephalins by cleavage of a Gly-Phe bond (PubMed:6349683, PubMed:17101991). Catalyzes cleavage of bradykinin, substance P and neurotensin peptides (PubMed:6208535). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:6349683, PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)) (PubMed:2531377, PubMed:2972276, PubMed:16254193). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).

Product Properties

• Clonality: Polyclonal
• Clone Designation: [R03643]
• Molecular Weight: 85514
• NCBI: 4311
• UniProt: P08473
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.