Catenin delta-1, Clone: [R03701], Rabbit, Polyclonal

Product Overview

• Article Name: Catenin delta-1, Clone: [R03701], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP22436A
• Supplier Catalog Number: AP22436a
• Alternative Catalog Number: ABT-AP22436A-200UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Alternative Names: Catenin delta-1, Cadherin-associated Src substrate, CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384

Product Description

Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed:14610055, PubMed:20371349). Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics (PubMed:10207085, PubMed:20371349). Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (PubMed:17344476).

Product Properties

• Clonality: Polyclonal
• Clone Designation: [R03701]
• Molecular Weight: 108170
• NCBI: 1500
• UniProt: O60716
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.