CD45 antibody, Clone: [R03408], Rabbit, Polyclonal

Product Overview

• Article Name: CD45 antibody, Clone: [R03408], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP22447A
• Supplier Catalog Number: AP22447a
• Alternative Catalog Number: ABT-AP22447A-200UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Alternative Names: Receptor-type tyrosine-protein phosphatase C, 3.1.3.48, Leukocyte common antigen, L-CA, T200, CD45, PTPRC (HGNC:9666), CD45

Product Description

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).

Product Properties

• Clonality: Polyclonal
• Clone Designation: [R03408]
• Molecular Weight: 147486
• NCBI: 5788
• UniProt: P08575
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Target: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.