FGL1 antibody, Clone: [R03133], Rabbit, Polyclonal

Product Overview

• Article Name: FGL1 antibody, Clone: [R03133], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP22464A
• Supplier Catalog Number: AP22464a
• Alternative Catalog Number: ABT-AP22464A-200UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Alternative Names: Fibrinogen-like protein 1, HP-041, Hepassocin, HPS, Hepatocyte-derived fibrinogen-related protein 1, HFREP-1, Liver fibrinogen-related protein 1 {ECO:0000303|Ref.3}, LFIRE-1 {ECO:0000303|Ref.3}, FGL1 {ECO:0000303|PubMed:18039467, ECO:0000312|HGNC:HGNC:3695}

Product Description

Immune suppressive molecule that inhibits antigen-specific T- cell activation by acting as a major ligand of LAG3 (PubMed:30580966). Responsible for LAG3 T-cell inhibitory function (PubMed:30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966). Secreted by, and promotes growth of, hepatocytes (PubMed:11470158, PubMed:19880967).

Product Properties

• Clonality: Polyclonal
• Clone Designation: [R03133]
• Molecular Weight: 36379
• NCBI: 2267
• UniProt: Q08830
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.