Gasdermin-E antibody, Clone: [R03173], Rabbit, Polyclonal

Product Overview

• Article Name: Gasdermin-E antibody, Clone: [R03173], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP22465A-EV
• Supplier Catalog Number: AP22465a-ev
• Alternative Catalog Number: ABT-AP22465A-EV-50UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse
• Alternative Names: Gasdermin-E, Inversely correlated with estrogen receptor expression 1, ICERE-1, Non-syndromic hearing impairment protein 5, Gasdermin-E, N-terminal, GSDME-NT, Gasdermin-E, C-terminal, GSDME-CT, GSDME {ECO:0000303|PubMed:28459430, ECO:0000312|HGNC:HGNC:2810}

Product Description

[Gasdermin-E]: Precursor of a pore-forming protein that converts non-inflammatory apoptosis to pyroptosis (PubMed:27281216, PubMed:28459430, PubMed:33852854, PubMed:35594856, PubMed:36607699). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-E, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:28459430).

Product Properties

• Clonality: Polyclonal
• Clone Designation: [R03173]
• Molecular Weight: 54555
• NCBI: 1687
• UniProt: O60443
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.