p53(S315) Antibody, Clone: [R04091NP], Rabbit, Polyclonal
Catalog Number:
ABT-AP22475A
Product Overview
Article Name:
p53(S315) Antibody, Clone: [R04091NP], Rabbit, Polyclonal
Biozol Catalog Number:
ABT-AP22475A
Supplier Catalog Number:
AP22475a
Alternative Catalog Number:
ABT-AP22475A-200UL
Manufacturer:
Abcepta
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human, Mouse
Alternative Names:
Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, TP53, P53
Product Description
Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence (PubMed:11025664, PubMed: 12524540, PubMed: 12810724, PubMed: 15186775, PubMed: 15340061, PubMed: 17317671, PubMed: 17349958, PubMed: 19556538, PubMed: 20673990, PubMed: 20959462, PubMed: 22726440, PubMed: 24051492, PubMed: 24652652, PubMed: 35618207, PubMed: 36634798, PubMed: 38653238, PubMed: 9840937). Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type (PubMed: 11025664, PubMed: 12524540, PubMed: 12810724, PubMed: 15186775, PubMed: 15340061, PubMed: 17189187, PubMed: 17317671, PubMed: 17349958, PubMed: 19556538, PubMed: 20673990, PubMed: 20959462, PubMed: 22726440, PubMed: 24051492, PubMed: 24652652, PubMed: 38653238, PubMed: 9840937). Negatively regulates cell division by controlling expression of a set of genes required for this process (PubMed: 11025664, PubMed: 12524540, PubMed: 12810724, PubMed: 15186775, PubMed: 15340061, PubMed: 17317671, PubMed: 17349958, PubMed:
Product Properties
Clonality:
Polyclonal
Clone Designation:
[R04091NP]
Molecular Weight:
43653
NCBI:
7157
UniProt:
P04637
Form:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Target:
This p53(S315) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human p53(S315).