NPM1 Antibody (C-term), Rabbit, Polyclonal

Product Overview

• Article Name: NPM1 Antibody (C-term), Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP2834B-EV
• Supplier Catalog Number: AP2834b-ev
• Alternative Catalog Number: ABT-AP2834B-EV-80UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: FC, IF, IHC-P, WB
• Species Reactivity: Human
• Alternative Names: Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM

Product Description

NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.

Product Properties

• Clonality: Polyclonal
• Clone Designation: [RB17470]
• Molecular Weight: 32575
• NCBI: 4869
• UniProt: P06748
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Target: This NPM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human NPM1.
• Antibody Type: Polyclonal Antibody