Phospho-BACE(S498) Antibody, Clone: [RB7137], Rabbit, Polyclonal

Product Overview

• Article Name: Phospho-BACE(S498) Antibody, Clone: [RB7137], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP3032A
• Supplier Catalog Number: AP3032a
• Alternative Catalog Number: ABT-AP3032A-400UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: IHC-P, WB
• Species Reactivity: Human
• Alternative Names: Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149

Product Description

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimers disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.

Product Properties

• Clonality: Polyclonal
• Clone Designation: [RB7137]
• Molecular Weight: 55764
• NCBI: 23621
• UniProt: P56817
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target: This BACE Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S498 of human BACE.