PERK Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51183
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| Article Name: | PERK Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51183 |
| Supplier Catalog Number: | AP51183 |
| Alternative Catalog Number: | ABT-AP51183-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, ICC, IHC-P, IP, WB |
| Species Reactivity: | Human |
| Alternative Names: | Eukaryotic translation initiation factor 2-alpha kinase 3, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, HsPEK, EIF2AK3, PEK, PERK |
| Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1) (By similarity). |
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