EXO1 Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: EXO1 Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP51200
• Supplier Catalog Number: AP51200
• Alternative Catalog Number: ABT-AP51200-100UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, ICC, WB
• Species Reactivity: Human, Mouse
• Alternative Names: Exonuclease 1, hExo1, 31--, Exonuclease I, hExoI, EXO1, EXOI, HEX1

Product Description

5->3 double-stranded DNA exonuclease which may also possess a cryptic 3->5 double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch- containing DNA tracts directed by strand breaks located either 5 or 3 to the mismatch. Also exhibits endonuclease activity against 5-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

Product Properties

• Clonality: Polyclonal
• NCBI: 9156
• UniProt: Q9UQ84