Glucagon Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51225
Article Name: Glucagon Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51225
Supplier Catalog Number: AP51225
Alternative Catalog Number: ABT-AP51225-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, ICC, IHC-P, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Glucagon, Glicentin, Glicentin-related polypeptide, GRPP, Oxyntomodulin, OXM, OXY, Glucagon, Glucagon-like peptide 1, GLP-1, Incretin hormone, Glucagon-like peptide 1(7-37), GLP-1(7-37), Glucagon-like peptide 1(7-36), GLP-1(7-36), Glucagon-like peptide 2, GLP-2, GCG
Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability. Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.
Clonality: Polyclonal
NCBI: 2641
UniProt: P01275