MYO6 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51374
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| Article Name: | MYO6 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51374 |
| Supplier Catalog Number: | AP51374 |
| Alternative Catalog Number: | ABT-AP51374-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Unconventional myosin-VI, Unconventional myosin-6, MYO6, KIAA0389 |
| Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells. May act as a regulator of F-actin dynamics. May play a role in transporting DAB2 from the plasma membrane to specific cellular targets. Required for structural integrity of inner ear hair cells (By similarity). |
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