In January of 2021 a new lineage of SARS-CoV-2, known as P.1 and named Gamma variant, was discovered in Japan and later spread in Brazil. It is considered a VOC (variant of concern). This variant carries 10 mutations in spike protein, including N501Y, E484K and K417T in RBD, which can increase the affinity to the human ACE2 receptor. Enhanced transmission of the Gamma variant (P.1 lineage) was observed globally, which is 3.5 times more contagious as the original one. The Gamma variant affects the effectiveness of COVID19 vaccine and is resistant to neutralization to some extent due to the immune escape E484K mutation.
SARS-CoV-2 Spike 26P antibody is supplied in PBS containing 0.02% sodium azide.
Purity:
Anti-SARS-CoV-2 Spike 26P antibody is immunoaffinity chromatography purified IgG.
Target:
It detects Spike S1 proteins of SARS-CoV-2 WT and variants except gamma variant.
Antibody Type:
Monoclonal Antibody
Application Notes:
WB: 1 µg/mL. Antibody validated: Western Blot in human samples. Anti-SARS-CoV-2 Spike 26P antibody detects all other SARS-CoV-2 variant Spike S1 protein, but not SARS-CoV-2 Gamma variant Spike S1 protein by ELISA. All other applications and species not yet tested.
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