Non-structural protein 8, ORF8, ORF8 protein, covid-19, ns8, sars-cov-2
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF9c and ORF10. ORF8 may play a role in modulating host immune response (Probable). May play a role in blocking host IL17 cytokine by its interaction with host IL17RA (3).
SARS-CoV-2 (COVID-19) ORF8 antibody is supplied in PBS containing 0.02% sodium azide.
Purity:
SARS-CoV-2 (COVID-19) ORF8 Antibody is affinity chromatography purified via peptide column.
Target:
ORF8 Antibody is predicted to not cross-react with other coronavirus family members.
Antibody Type:
Polyclonal Antibody
Application Notes:
WB: 1 µg/mLAntibody validated: SARS-CoV-2 (COVID-19) ORF8 antibody can detect 2 ng of free peptide at 1 µg/mL in ELISA. It can detect SARS-CoV-2 ORF8 recombinant protein by WB. All other applications and species not yet tested.
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