GZMB Antibody (N-term) Blocking Peptide

Product Overview

• Article Name: GZMB Antibody (N-term) Blocking Peptide
• Biozol Catalog Number: ABT-BP6575A
• Supplier Catalog Number: BP6575a
• Alternative Catalog Number: ABT-BP6575A-500UG
• Manufacturer: Abcepta
• Category: Proteine/Peptide
• Alternative Names: Granzyme B, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E, GZMB, CGL1, CSPB, CTLA1, GRB

Product Description

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Product Properties

• NCBI: 3002
• UniProt: P10144
• Form: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
• Target: The synthetic peptide sequence used to generate the antibody AP6575a was selected from the N-term region of human GZMB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.