SERPIND1 is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in its gene are associated with heparin cofactor II deficiency.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP6706c was selected from the Center region of human SERPIND1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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