Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog, XPO1, CRM1
XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. It inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase. This protein also regulates NFAT and AP-1.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP6758b was selected from the C-term region of human XPO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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