Serine/threonine-protein kinase RIO2, RIO kinase 2, RIOK2
RIOK2 belongs to the protein kinase superfamily, RIO-type Ser/Thr kinase family. Serine/threonine protein kinases, such as RIOK2, phosphorylate the OH group of serine or threonine (which have similar sidechains). Activity of these protein kinases can be regulated by specific events (e.g. DNA damage), as well as numerous chemical signals, including cAMP/cGMP, Diacylglycerol, and Ca2+/calmodulin.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP7009b was selected from the C-term region of human RIOK2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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