PHB2 Blocking Peptide (Y248)

Product Overview

• Article Name: PHB2 Blocking Peptide (Y248)
• Biozol Catalog Number: ABT-BP7270E
• Supplier Catalog Number: BP7270e
• Alternative Catalog Number: ABT-BP7270E-500UG
• Manufacturer: Abcepta
• Category: Proteine/Peptide
• Alternative Names: Prohibitin-2, B-cell receptor-associated protein BAP37, D-prohibitin, Repressor of estrogen receptor activity, PHB2 {ECO:0000312|EMBL:AAH147661, ECO:0000312|HGNC:HGNC:30306}

Product Description

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.

Product Properties

• NCBI: 11331
• UniProt: Q99623
• Form: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
• Target: The synthetic peptide sequence is selected from aa 240-255 of HUMAN PHB2