DET1 is a component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP7271b was selected from the C-term region of human DET1 ANtibody (C-term). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular ass
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