Carbonic anhydrase-related protein 11, CA-RP XI, CA-XI, CARP XI, Carbonic anhydrase-related protein 2, CA-RP II, CARP-2, CA11, CARP2
CA11 belongs a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CA11 is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. This protein shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. The protein is most abundantly expressed in brain, and may play a general role in the central nervous system.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP7304b was selected from the C-term region of human CA11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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